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Rabbit Anti-Rat Reprimo (RPRM) Polyclonal Antibody

Cat. No.VD3N368

Product TypeVeterinary Antibodies

Size

Product Overview

BioVenic rabbit polyclonal antibody is specific for rat reprimo. It is purified by protein A. It can be applied to WB, IHC, ICC and IP assays of rat reprimo.

Specifications

Application WB; IHC; ICC; IP
Clonality Polyclonal
Classification Primary Antibody
Clone C1N119
Host Rabbit
Target Species Rat
Species Reactivity Rat
Specificity Rat Reprimo
Isotype IgG
Immunogen Recombinant protein of rat reprimo
Purification Purified by Protein A
Concentration 0.5 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.02% Sodium Azide
Buffer Phosphate Buffered Saline, pH 7.4, with 50% glycerol
Physical State Liquid

Target Information

Rat Reprimo (RPRM) is a protein involved in cell cycle regulation. It targets the G1/S phase transition by inhibiting the activity of cyclin-dependent kinases (CDKs), specifically CDK4 and CDK6. Reprimo plays a crucial role in maintaining cell cycle checkpoints and preventing uncontrolled cell proliferation. Its activity is essential for ensuring proper DNA replication and repair, contributing to genomic stability. The specific interaction of Reprimo with CDKs makes it a valuable target for antibody development to enhance detection and monitoring in cell biology and cancer research, supporting studies on cell cycle regulation and related pathologies.

Target Rat Reprimo
Target Synonym Candidate Mediator of The p53 Dependent G2 Arrest
Gene ID 680110
UniProt ID Q5BJN9

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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