This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Rabbit Anti-Mouse Fibroblast Growth Factor 8 (FGF8) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse fibroblast growth factor 8, androgen induced. It is purified by protein A. It can be applied to WB, IHC, ICC and IP assays of mouse fibroblast growth factor 8, androgen induced.
Specifications
Target Information
Mouse fibroblast growth factor 8, androgen-induced (FGF8) is a 23-kDa secreted growth factor predominantly expressed in murine androgen-sensitive tissues (prostate, testis) and developing embryos. It signals via FGF receptors (FGFRs) to activate PI3K-AKT and MAPK pathways, regulating cell proliferation, differentiation, and tissue morphogenesis. Critical for murine prostate development, spermatogenesis, and embryonic limb/pattern formation, it modulates androgen-dependent tissue homeostasis. Dysregulated overexpression associates with prostate cancer progression, tumor angiogenesis, and developmental defects in mouse models, as aberrant signaling drives malignant transformation. As a key mediator of androgen-responsive growth signaling, mouse FGF8 is a critical target for studying prostate pathobiology, developmental biology, and anti-androgen/anti-cancer therapeutics.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.