This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Preclinical In Vivo Solution
Introduction
Connecting Molecule to Mechanism with Unparalleled Confidence. Stuck on model consistency or bogged down by preclinical validation? BioVenic Preclinical In Vivo Solutions strengthen your R&D efforts by providing animal model construction, deep phenotyping and high throughput biosample analysis. We are experts at turning your complex scientific questions into high quality reproducible data, optimizing your non-GLP preclinical workflow and de-risking your decision-making process.
Non-GLP In Vivo Model Development
BioVenic's non-GLP in vivo animal model development services cater to the critical stages of drug discovery, vaccine screening, and gene/cell research. We leverage a diverse library of established protocols and offer bespoke customization to meet specific research objectives.
By Induction Method:
- Diet-Induced Models
- Genetic Engineering
- Surgical Intervention
- Chemical Induction
- Biological Induction
By Disease Area:
Specialized Animal Biosampling Services
Precision in data starts with precision in sampling. BioVenic technicians employ refined techniques to ensure sample integrity.
Veterinary Pathology Services
Visualize the microscopic impact of your test articles. BioVenic provides high-resolution imaging and specialized staining to evaluate organ-specific effects (Heart, Liver, Kidney, etc.), essential for confirming model success and preliminary efficacy.
Animal Behavioral Analysis Services
Beyond basic intake monitoring, BioVenic Animal Behavioral Analysis Service offers deep insights into functional outcomes:
Routine: Food/water intake, circadian rhythm.
Advanced: Emotional profiling, motor coordination, cognitive function, and motivational behavior in rodents.
Animal In Vivo Imaging Services
Biovenic Animal In Vivo Imaging Services utilizes non-invasive technology to track progression in real-time:
Modalities: Optical imaging (BLI/FLI), Bone Mineral Density (BMD), X-Ray, Ultrasound, CT, MRI, and ECG.
Application: Long-term efficacy monitoring and internal structural safety assessments.
Animal Cellular Biology Services
BioVenic Animal Cellular Biology Services bridge the gap between whole-body observations and cellular mechanisms.
- Primary Cell Isolation: Custom extraction from specific tissues.
- Analysis: Flow cytometry, cytokine profiling, and 3D cell/organoid culture to decode the micro-environments driving in vivo results.
Animal Preclinical Pharmacokinetics (PK) Services
BioVenic Animal Preclinical Pharmacokinetics (PK) Services help understand the life cycle of your compound (ADME): Absorption, Distribution, Metabolism, and Excretion.
Key Parameters: Half-life (t1/2), bioavailability, and drug-drug interactions.
Route Optimization: Comparative data for Oral (PO), Injection (IV/IP), or Subcutaneous (SC) delivery.
Animal Preclinical Pharmacodynamics (PD) Services
BioVenic expert team measures the physiological, molecular, and behavioral responses triggered by your agent. By integrating behavioral scores, imaging, biochemical markers, and histopathology, we provide a holistic view of the dose-response relationship.
Our Species Expertise
We support a wide array of models, helping you select the most relevant species for your specific research goals.
|
|
|
Standard Rodents
Other Species
Advantages of BioVenic Animal Preclinical In Vivo Solution
Multidisciplinary Expertise:
A team of senior zoologists, pharmacologists, and pathologists dedicated to protocol optimization.
Turnkey Delivery:
From initial model construction to final analytical reporting and sample storage-allowing you to focus entirely on strategic decisions.
Integrated Resource Ecosystem:
Access to our vast catalog of customized antibodies, proteins, and cell lines for a seamless transition from in vitro to in vivo.
Ethics & Welfare:
Services are conducted in strict alignment with standards, prioritizing animal welfare and data integrity.
FAQs
Q: Can you provide specific Gene Knock-out (KO) or Knock-in (KI) models?
A: Yes. Our gene-editing platform supports the construction of KO, KI, conditional KO, and humanized models
Q: What is the typical project timeline?
A: Timelines vary based on model complexity; standard chemical induction is faster than complex transgenic breeding or large animal longitudinal studies.
Q: Can we select the age and sex of the animals?
A: We customize cohorts based on weight, age, and sex, all of which are documented in the final report.
Q: Do I need to provide the animals or reagents?
A: We offer two flexible options: 1. Full-service (we supply all animals and reagents) or 2. Client-supplied (you provide the specific test article, and we manage reception, storage, and administration).
Q: Do you sell live animals?
A: No, we do not provide live animals for sale. We are a service provider specializing in model construction and the subsequent execution of research studies on those models.
Q: Are your studies GLP-compliant?
A: Our platform currently focuses exclusively on high-quality non-GLP preclinical research and discovery services.
Contact Us
Looking for advanced preclinical development support? At BioVenic we strive to deliver the quality data you require to confidently progress your pipeline. Our in vivo services encompass custom animal model engineering to advanced PD/PK analysis. Reach out to us for a technical consultation or project quote.