Nephropathy has become one of the major threats to the health of companion animals such as dogs and cats. By the time an animal develops symptoms associated with nephropathy, severe kidney damage has occurred. Therefore, early detection is of great significance for slowing down the development of nephropathy, increasing the lifespan, and improving the life quality of animals. BioVenic, as a top development company for animal disease in vitro diagnostics solutions, has been paying attention to animal nephropathy and has mastered a wide range of nephropathy biomarkers. Our commitment is to provide clients with a comprehensive and tailor-made animal nephropathy diagnostics development service to help advance animal health and veterinary research.
What Is Animal Nephropathy?▼
Animal nephropathy pertains to any aberrant kidney condition or disease found in various animals including mammals, birds, reptiles, and amphibians. It's noteworthy to highlight that this service predominantly caters to companion animals, with a particular focus on canines and felines. Nephropathy encompasses a spectrum of acute and chronic kidney ailments, attributed to a range of factors such as infections, toxins, genetic predisposition, and other etiological agents.
Animal Nephropathy Diagnostics Development Services
Contemporary approaches for identifying kidney disorders in mammals, notably canines, encompass kidney ultrasound, biopsy, and assessment of urine protein/creatinine ratios. Biopsies entail invasiveness, and creatinine measurements exhibit limited accuracy until renal failure reaches stage III, resulting in substantial tissue damage by that juncture. At BioVenic, we specialize in advancing animal nephropathy diagnostics, facilitating early detection to preempt the advancement of kidney disease. The crux of our service is encapsulated in the ensuing key aspects.
Biomarkers and Indicators Screening
Our experts help customers screen for statistically significant differential metabolites or proteins through high-throughput screening methods such as genome, transcriptome, or proteome. After a series of complex bioinformatics analyses, biomarkers or indicators that reflect kidney function are screened out.
Nephropathy Diagnostics Assay Development
Utilizing advanced technology platforms, we develop laboratory diagnostic methods for customers to reveal changes in kidney performance, including immunodiagnostics methods such as ELISA, Western blot, and IFA, molecular diagnostics methods such as NGS, microarray, and urinalysis.
Diagnostic Reagent Research
We provide customers with high-quality reagent research and development services based on different nephropathy diagnostics methods. For immunodiagnosis, we provide antigens, antibodies, markers, buffers and other reagents. For molecular diagnostics methods, we provide a variety of reagents and accessories such as primers and enzymes. We also offer all components covered in urine test strip development.
Optimization and Kit Development
We have rich R&D experience and help customers optimize various nephropathy diagnostics methods based on immunodiagnostics, molecular diagnostics, and urinalysis. In addition, we provide our customers with diagnostics kit development services that meet all aspects of their requirements.
Common Animal Nephropathy Biomarkers and Indicators
We provide one-stop nephropathy diagnostics solutions for a rich set of biomarkers and indicators, including but not limited to those in the table.▼
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Kidney Disease
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Detected Indicators and Biomarkers
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Assay Development
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Chronic kidney disease (CKD)
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Urine specific gravity, creatinine (CREA), urine protein, blood urea nitrogen (BUN), urea, white blood cell count (WBC), urine pH, symmetric dimethylarginine (SDMA), cystatin C (CysC), neutrophil gelatinase-associated lipocalin (NGAL), serum concentrations of leptin and adiponectin, etc.
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Hematology analysis, urinalysis, ELISA, IFA, WB
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Acute kidney injury (AKI)
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Monocyte chemoattractant protein-1 (MCP-1), kidney injury molecule-1 (KIM-1), NGAL, liver fatty acid binding protein (L-FABP), calreticulin, alpha-1 microglobulin (α1M), TIM -1/KIM-1/HAVCR, lipocalin-2/NGAL, osteopontin, CysC, clusterin, CXCL10/IP-10, RBP-4, fetuin A/AHSG and TFF3, etc.
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ELISA, IFA, WB
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Diabetic Kidney Disease (DKD)
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Urine albumin creatinine ratio (Uac)R, glomerular filtration rate (GFR)
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Hematology analysis, urinalysis
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kidney Inflammation
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Interleukin-18 (IL-18), an 18-kDa proinflammatory cytokine, and a member of the IL-1 superfamily
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ELISA, IFA, WB
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Renal Tubular Injury
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Epidermal growth factor (EGF), insulin-like growth factor-binding protein 7 (IGFBP-7), IL, KIM-1, L-FABP, MCP-1, NGAL, procollagen type III N-terminal propeptide (PIIINP), tissue inhibitor of metalloproteinases-2 (TIMP-2), uromodulin (UMOD), etc.
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ELISA, IFA, WB
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Kidney Disease Arising from Bacterial Infection
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Anaplasma sp., Ehrlichia sp., Leptospira sp., Escherichia sp., Borrelia sp., etc.
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ELISA, IFA, PCR, NGS, microarray
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Our Service Process
Why Choose Us?
Early Identification
Our diagnostics development solutions prioritize early markers of nephropathy in animals, helping animal health researchers achieve early detection of nephropathy.
Precision
Employing cutting-edge laboratory technology, our service ensures the precise screening and analysis of biomarkers associated with animal kidney diseases, furnishing veterinary researchers with a dependable diagnostic framework.
Encompassing Solution
Our developmental offerings span an array of animal kidney ailments, offering exhaustive diagnostic insights to veterinary researchers, thereby enabling a comprehensive understanding of the conditions at hand.
BioVenic is committed to reshaping the landscape of animal kidney health assessment via our animal nephropathy in vitro diagnostic development services. Collaborating with us enables you to not only oversee your animals' well-being but also play a pivotal role in propelling the entire field of veterinary medicine forward. connect with us to delve deeper into our offerings and explore the vast potential of our services.
