Formulation Solution for Veterinary Vaccine Development

The appropriate choice of antigens, adjuvant development, delivery system development, and administration route optimization are closely interrelated in veterinary vaccine development. These elements work together to enhance the immunogenicity, efficacy, and administration efficiency of vaccines. BioVenic provides comprehensive solutions for formulation development, aiming to offer more than just antigen-related services and provide you with a convenient experience for the later stages of veterinary vaccine development.

Our Services

Administration Route Optimization

Veterinary vaccines can be administered through various routes, and the specific choice typically depends on the vaccine type, target animal, and desired immunization effects. BioVenic provides suitable animal models for in vivo experiments. We assess the safety, effectiveness, and immunogenicity under different administration methods to offer formulation development services and guidance for your veterinary vaccine delivery approach.

Delivery System Development

Various carrier systems for antigen delivery have been studied, including liquid systems (such as emulsions), particulate delivery systems (such as liposomes, microparticles, nanoparticles, and virosomes), as well as viral or bacterial vectors. BioVenic provides services for the development of delivery systems that enhance antigen uptake by antigen-presenting cells and improve antigen expression. In order to successfully develop veterinary vaccines, we capitalize on the loading capacity and specific properties of carriers to enhance the efficacy of veterinary vaccine formulations. Additionally, we optimize existing delivery systems by addressing issues such as the safety of biological carriers and the targeting specificity of chemical carriers.

Fig.1 Delivery systems based on different nanoparticles are widely used in veterinary vaccine development. ¹

Adjuvant Development

Adjuvants are widely used in the development of veterinary vaccines, particularly inactivated vaccines, subunit vaccines, and nucleic acid vaccines, serving to enhance the immunogenicity of these vaccines. Adjuvants can encompass a variety of chemical substances or biological agents, including but not limited to mineral oils, liposomes, proteins, polysaccharides, nucleic acids, and more. However, the use of adjuvants may also lead to adverse reactions in vaccinated animals, potentially impacting the safety of the final veterinary vaccines.

BioVenic provides services for adjuvant strategy formulation, tailoring the choice of adjuvant types and combinations to your specific vaccine requirements. Additionally, we offer adjuvant optimization services, evaluating the efficacy and safety of different adjuvants and taking your input into account to formulate adjuvant components, ensuring that vaccinated animals achieve a high-quality immune response.

Why Choose Us?

Vaccine formulation is a key point that need to be focused on to enhance immunogenicity and stability in veterinary vaccine development. BioVenic provides a complete set of veterinary vaccine formulation solutions, always prioritizing the safety of veterinary vaccines while optimizing formulations. If you have any thoughts about investing efforts in vaccine formulation, please do not hesitate to contact us!

Reference

1. Bezbaruah, Rajashri, et al. "Nanoparticle-based delivery systems for vaccines." Vaccines 10.11 (2022): 1946.