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Rabbit Anti-Mouse Angiotensin I Converting Enzyme 2 (ACE2) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse angiotensin I converting enzyme 2. It is purified by protein A. It can be applied to WB, IHC, ICC and IP assays of mouse angiotensin I converting enzyme 2.
Specifications
Target Information
Mouse angiotensin I converting enzyme 2 (ACE2) is a 80-kDa transmembrane metallopeptidase predominantly expressed in mouse lung, heart, kidney, and intestinal epithelial cells. It regulates the renin-angiotensin system (RAS) by cleaving angiotensin II to angiotensin-(1-7), balancing vasoconstriction/vasodilation and reducing tissue inflammation. As a key entry receptor for coronaviruses (e.g., SARS-CoV, SARS-CoV-2) in mice, it mediates viral attachment and cell entry. Critical for murine cardiovascular homeostasis, fluid balance, and mucosal barrier function, its dysregulation links to hypertension, heart failure, and viral pathogenesis. As a dual-function mediator of RAS and viral entry, mouse ACE2 is a critical target for studying cardiovascular biology, inflammatory disorders, and antiviral therapeutics.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.