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Rabbit Anti-Mouse Calcium Sensing Receptor (CASR) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse calcium sensing receptor. It is purified by protein A. It can be applied to WB, IHC, ICC and IP assays of mouse calcium sensing receptor.
Specifications
Target Information
Mouse calcium sensing receptor (CaSR) is a 120-kDa G protein-coupled receptor (GPCR) predominantly expressed in murine parathyroid glands, kidneys, and gastrointestinal tract. It detects extracellular calcium concentrations, initiating signaling cascades that regulate parathyroid hormone secretion, renal calcium excretion, and intestinal calcium absorption. Critical for maintaining systemic calcium-phosphate homeostasis and bone metabolism in mice, it also modulates cell proliferation, differentiation, and inflammatory responses in diverse tissues. Dysregulated activity associates with hyperparathyroidism, hypocalcemia, and bone disorders. As a key mediator of calcium signaling and metabolic balance, mouse CaSR is a critical target for studying mineral homeostasis, skeletal pathobiology, and GPCR-targeted therapeutics.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.