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Rabbit Anti-Mouse Dynamin 1 (DNM1) Polyclonal Antibody

Cat. No.VD4N91

Product TypeVeterinary Antibodies

Size

Product Overview

BioVenic rabbit polyclonal antibody is specific for mouse dynamin 1. It is purified by protein A. It can be applied to WB and IHC assays of mouse dynamin 1.

Specifications

Application WB; IHC
Clonality Polyclonal
Classification Primary Antibody
Clone C3N163
Host Rabbit
Target Species Mouse
Species Reactivity Mouse
Specificity Mouse Dynamin 1
Isotype IgG
Immunogen Recombinant protein of mouse dynamin 1
Purification Purified by Protein A
Concentration 0.5 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.05% Proclin 300
Buffer 0.01M Phosphate Buffered Saline, pH 7.4, with 50% glycerol
Physical State Liquid

Target Information

Mouse dynamin 1 is a 97 kDa neuronal GTPase whose coiled-coil neck links four oligomerization domains; GTP hydrolysis twists the helix to sever clathrin-coated vesicles. A solvent-exposed 15-aa "PRS" loop (aa 518-532) between GED and GTPase domains forms a β-hairpin unique among dynamin isoforms. Antibodies to this loop trace native dynamin 1 in synaptic terminals, growth cones, and adrenal chromaffin cells, giving crisp vesicle collars and single-band blots without cross-reaction to dynamin 2 or 3.

Target Mouse Dynamin 1
Gene ID 13429
UniProt ID P39053

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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