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Rabbit Anti-Bovine Bone Morphogenetic Protein 2 (BMP2) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for bovine bone morphogenetic protein 2. It is purified by protein A. It can be applied to WB, IHC, ICC and IP assays of bovine bone morphogenetic protein 2.
Specifications
Target Information
Bovine bone morphogenetic protein 2 (BMP-2) is a secreted disulfide-linked homodimer that binds type I (ALK-2/3/6) and type II BMP receptors, initiating SMAD1/5/8 phosphorylation and osteogenic transcription. It targets mesenchymal progenitors, driving their differentiation into osteoblasts and chondrocytes while also promoting extracellular matrix mineralization. The mature 114-aa ligand presents a solvent-exposed β-sheet epitope conserved across bovine, human and rodent sequences-ideal for antibody generation. Anti-BMP-2 immunoreagents enable precise localization of osteoinductive signals in bone grafts, cartilage repair constructs and ectopic calcification sites without cross-reacting with other TGF-β superfamily members.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.