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Rabbit Anti-Chicken Osteocalcin (OC) Polyclonal Antibody

Cat. No.VD3N721

Product TypeVeterinary Antibodies

Size

Product Overview

BioVenic rabbit polyclonal antibody is specific for chicken osteocalcin. It is purified by protein A. It can be applied to WB, IHC, ICC and IP assays of chicken osteocalcin.

Specifications

Application WB; IHC; ICC; IP
Clonality Polyclonal
Classification Primary Antibody
Clone C2N121
Host Rabbit
Target Species Chicken
Species Reactivity Chicken
Specificity Chicken Osteocalcin
Isotype IgG
Immunogen Recombinant protein of chicken osteocalcin
Purification Purified by Protein A
Concentration 0.5 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.05% Proclin 300
Buffer 0.01M Phosphate Buffered Saline, pH 7.4, with 50% glycerol
Physical State Liquid

Target Information

Chicken osteocalcin is a 6 kDa, 49-residue vitamin-K-dependent protein synthesized exclusively by mature osteoblasts. It targets a conserved, species-restricted epitope within its three γ-carboxyglutamate (Gla) residues, which bind hydroxyapatite and anchor the peptide to the bone matrix. The compact α-helical structure exposes a unique C-terminal loop ideal for antibody generation; anti-osteocalcin immunoreagents detect intact molecule in serum, bone extracts and fixed tissue sections without cross-reacting with other Gla proteins, providing a precise read-out of osteoblast activity and matrix mineralization.

Target Chicken Osteocalcin
Target Synonym BGLAP; OT; BGP; Bone Gla Protein; Bone Gamma-Carboxyglutamate Protein
Gene ID 396348
UniProt ID P02822

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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