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Mouse Anti-Rat Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Monoclonal Antibody
Product Overview
BioVenic mouse monoclonal antibody is specific for rat proprotein convertase subtilisin/kexin type 9. It is purified by protein A and protein G. It can be applied to WB, IHC, ICC and IP assays of rat proprotein convertase subtilisin/kexin type 9.
Specifications
Target Information
Rat Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) is a secreted serine protease that binds hepatic LDL receptors, directing them to lysosomal degradation and thereby raising plasma LDL-cholesterol. Synthesized mainly in liver and intestine, PCSK9 circulates in plasma and interacts with receptors on hepatocytes, modulating cholesterol uptake. Loss-of-function lowers LDL, while gain-of-function promotes hypercholesterolemia. As a key regulator of lipoprotein clearance, PCSK9 is an important target for studies of lipid metabolism and atherosclerosis.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.