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Rabbit Anti-Mouse Succinate Dehydrogenase Complex Subunit D (SDHD) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse succinate dehydrogenase complex subunit d. It is purified by protein A. It can be applied to WB, IHC, ICC and IP assays of mouse succinate dehydrogenase complex subunit d.
Specifications
Target Information
Mouse succinate dehydrogenase complex subunit D (SDHD) anchors the electron-transferring SDHC subunit to the inner mitochondrial membrane, shaping the hydrophobic belt that seals ubiquinone reduction. This 17 kDa integral membrane protein contributes the heme ligand that fine-tunes electron flux from succinate to coenzyme Q, stabilizing Complex II against oxidative stress. Its tyrosine-rich matrix loops create a docking platform for supernumerary factors that modulate tricarboxylic acid cycle flux and mitochondrial morphology. SDHD's exposed C-terminal tail offers a specific, conformation-sensitive epitope for quantitative detection of intact Complex II in respirasome assemblies, immunoprecipitation, and super-resolution mapping of mitochondrial ultrastructure.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.