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Rabbit Anti-Mouse Forkhead Box Protein O1 (FOXO1) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse forkhead box protein O1. It is purified by protein A. It can be applied to WB, IHC, ICC and IP assays of mouse forkhead box protein O1.
Specifications
Target Information
Mouse forkhead box protein O1 (FOXO1) is a transcription factor that regulates genes controlling metabolism, oxidative stress and cell-cycle checkpoints. Phosphorylation by AKT promotes its nuclear exclusion, whereas dephosphorylation allows DNA binding and transcriptional activation. FOXO1 is broadly expressed in insulin-sensitive tissues, liver and vasculature, making it a reliable read-out for nutrient-sensing pathways. Specific antibody staining provides precise sub-cellular localization and quantitative assessment of signaling shifts in metabolic, aging and cancer models.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.