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Rabbit Anti-Rat Phosphodiesterase 3A (PDE3A) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for rat phosphodiesterase 3A, cGMP inhibited. It is purified by protein A. It can be applied to WB, IHC, ICC and IP assays of rat phosphodiesterase 3A, cGMP inhibited.
Specifications
Target Information
Rat Phosphodiesterase 3A, cGMP-inhibited (PDE3A) is a membrane-associated enzyme that specifically hydrolyzes cAMP, thereby reducing intracellular cAMP levels and modulating PKA activity. PDE3A is highly expressed in the heart, vascular smooth muscle, and platelets, where it regulates cardiac contractility, vascular tone, and platelet aggregation. Its activity is inhibited by cGMP, providing cross-talk between cyclic nucleotide pathways. As a key regulator of cAMP signaling, PDE3A is an important target for studies of cardiovascular function and potential therapeutic applications in heart failure and hypertension.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
