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Rabbit Anti-Rat Glutamate Cysteine Ligase (GCLC) Polyclonal Antibody

Cat. No.VD3N414

Product TypeVeterinary Antibodies

Size

Product Overview

BioVenic rabbit polyclonal antibody is specific for rat glutamate cysteine ligase. It is purified by protein A. It can be applied to WB, IHC, ICC and IP assays of rat glutamate cysteine ligase.

Specifications

Application WB; IHC; ICC; IP
Clonality Polyclonal
Classification Primary Antibody
Clone C1N165
Host Rabbit
Target Species Rat
Species Reactivity Rat
Specificity Rat Glutamate Cysteine Ligase
Isotype IgG
Immunogen Recombinant protein of rat glutamate cysteine ligase
Purification Purified by Protein A
Concentration 0.5 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.02% Sodium Azide
Buffer Phosphate Buffered Saline, pH 7.4, with 50% glycerol
Physical State Liquid

Target Information

Rat Glutamate Cysteine Ligase, Catalytic (GCLC) is a key enzyme in the synthesis of glutathione, an essential antioxidant in cells. It catalyzes the first and rate-limiting step in glutathione production, combining glutamate and cysteine to form gamma-glutamylcysteine. GCLC is crucial for maintaining cellular redox balance and protecting cells from oxidative stress. This enzyme is expressed in various tissues and plays a vital role in detoxification processes, contributing to overall cellular defense mechanisms against reactive oxygen species.

Target Rat Glutamate Cysteine Ligase
Target Synonym GCS; GLCL; GLCLC; Gamma-glutamylcysteine synthetase; Gamma-ECS
Gene ID 25283
UniProt ID P19468

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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