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Rabbit Anti-Rat 5'-Nucleotidase Cytosolic III (NT5C3) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for rat 5'-nucleotidase, cytosolic III. It is purified by protein A. It can be applied to WB, IHC, ICC and IP assays of rat 5'-nucleotidase, cytosolic III.
Specifications
Target Information
Rat 5'-nucleotidase, cytosolic III (NT5C3, cN-III) is a 34 kDa metal-dependent phosphatase whose α-β sandwich active site converts AMP/IMP to adenosine/inosine, balancing nucleotide pools. A solvent-exposed 15-aa "KVE" loop (aa 145-159) between β6 and α4 folds into a β-hairpin unique among rat nucleotidases, presenting a conformational epitope preserved after fixation. Affinity-purified antibodies targeting this loop trace native NT5C3 in hepatic cytosol, renal proximal tubules, and splenic lymphocytes, delivering crisp diffuse staining and single-band clarity on immunoblots with no cross-reaction to NT5C1 or NT5C2.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
