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Rabbit Anti-Mouse Calcium Channel Voltage Dependent L-Type Alpha 1S Subunit (CACNa1S) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse calcium channel, voltage dependent, L-type, alpha 1S subunit. It is purified by protein A. It can be applied to WB, IHC, ICC and IP assays of mouse calcium channel, voltage dependent, L-type, alpha 1S subunit.
Specifications
Target Information
Mouse L-type voltage-gated calcium channel α1S (CACNA1S) is the pore-forming subunit of the dihydropyridine-sensitive skeletal muscle CaV1.1 channel. It conducts calcium influx that couples sarcolemmal depolarization to ryanodine-receptor-mediated sarcoplasmic reticulum calcium release, initiating excitation-contraction coupling. The α1S subunit is expressed exclusively in skeletal muscle and serves as a scaffold for the β, α2δ, and γ accessory subunits. As a critical mediator of muscle contraction and calcium homeostasis, CACNA1S is an important target for studies of muscle physiology, channelopathies, and neuromuscular disorders.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.