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Rabbit Anti-Mouse Transmembrane Protein 27 (TMEM27) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse transmembrane protein 27. It is purified by protein A. It can be applied to WB and IHC assays of mouse transmembrane protein 27.
Specifications
Target Information
Mouse transmembrane protein 27 (TMEM27), also known as collectrin, is a 22 kDa single-span membrane glycoprotein enriched in renal proximal tubules and pancreatic β-cells. Its extracellular domain captures luminal amino acids, while the short cytoplasmic tail clusters with trafficking adaptors to regulate endocytosis and surface recycling of the amino-acid transporter SLC6A19. The juxtamembrane stalk exposes a protease-accessible loop that releases a soluble ectodomain, enabling detection of both full-length and cleaved forms. Antibodies targeting the N-terminal ectodomain visualize apical brush-border staining, β-cell granule membranes, and circulating cleavage fragments without cross-reactivity to related ACE homologs.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.