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Rabbit Anti-Mouse Perilipin 1 (PLIN1) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse perilipin 1. It is purified by protein A. It can be applied to WB, IHC, ICC and IP assays of mouse perilipin 1.
Specifications
Target Information
Mouse perilipin 1 (PLIN1) is a 55-kDa lipid droplet (LD)-associated protein exclusively expressed in murine white and brown adipose tissue. It forms a protective coat around LDs, regulating lipolysis by interacting with adipose triglyceride lipase (ATGL) and hormone-sensitive lipase (HSL). Critical for maintaining lipid storage homeostasis and energy balance in mice, it modulates triglyceride synthesis, LD maturation, and lipolytic enzyme access to LD cores. Dysregulated expression associates with obesity, insulin resistance, and metabolic syndrome in murine models, as impaired PLIN1 function disrupts adipose tissue lipid handling. As a key mediator of adipocyte lipid metabolism, mouse PLIN1 is a critical target for studying metabolic pathobiology and developing therapeutics for obesity-related disorders.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.