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Rabbit Anti-Mouse Mindbomb Homolog 2 (MIB2) Polyclonal Antibody

Cat. No.VD3N497

Product TypeVeterinary Antibodies

Size

Product Overview

BioVenic rabbit polyclonal antibody is specific for mouse mindbomb homolog 2. It is purified by protein A. It can be applied to WB and IHC assays of mouse mindbomb homolog 2.

Specifications

Application WB; IHC
Clonality Polyclonal
Classification Primary Antibody
Clone C1N248
Host Rabbit
Target Species Mouse
Species Reactivity Mouse
Specificity Mouse Mindbomb Homolog 2
Isotype IgG
Immunogen Recombinant protein of mouse mindbomb homolog 2
Purification Purified by Protein A
Concentration 0.5 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.05% Proclin 300
Buffer 0.01M Phosphate Buffered Saline, pH 7.4, with 50% glycerol
Physical State Liquid

Target Information

Mouse Mindbomb Homolog 2 (Mib2) is an E3 ubiquitin ligase involved in the regulation of Notch signaling and endocytosis. It ubiquitinates Notch receptors, facilitating their internalization and degradation. Mib2 plays a crucial role in modulating Notch signaling, which is essential for cell fate determination and tissue development. Its activity ensures proper cellular responses to Notch signals and is implicated in various developmental processes. Mib2 is an important target for studying Notch signaling and related biological functions in mouse models.

Target Mouse Mindbomb Homolog 2
Target Synonym ZZANK1; SKD; ZZZ5; Skeletrophin; Novelzin
Gene ID 76580
UniProt ID Q8R516

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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