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Rabbit Anti-Mouse Sp100 Nuclear Antigen (Sp100) Polyclonal Antibody

Cat. No.VD3N632

Product TypeVeterinary Antibodies

Size

Product Overview

BioVenic rabbit polyclonal antibody is specific for mouse Sp100 nuclear antigen. It is purified by protein A. It can be applied to WB, IHC, ICC and IP assays of mouse Sp100 nuclear antigen.

Specifications

Application WB; IHC; ICC; IP
Clonality Polyclonal
Classification Primary Antibody
Clone C2N32
Host Rabbit
Target Species Mouse
Species Reactivity Mouse
Specificity Mouse Sp100 Nuclear Antigen
Isotype IgG
Immunogen Recombinant protein of mouse Sp100 nuclear antigen
Purification Purified by Protein A
Concentration 1 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.05% Proclin 300
Buffer 0.01M Phosphate Buffered Saline, pH 7.4, with 50% glycerol
Physical State Liquid

Target Information

Mouse Sp100 Nuclear Antigen is a constituent of promyelocytic leukemia nuclear bodies, anchoring chromatin-remodeling and transcriptional machinery. It modulates gene expression by recruiting chromatin modifiers and restricting viral replication, maintaining genomic integrity. Sp100 shuttles between nucleoplasmic speckles and target promoters, coordinating interferon-inducible responses. Its broad tissue distribution and dynamic relocation make it a reliable marker for nuclear architecture studies. Antibodies to Sp100 enable precise visualization of sub-nuclear compartments and interferon pathways in mouse models.

Target Mouse Sp100 Nuclear Antigen
Target Synonym Speckled 100 kDa; Nuclear dot-associated Sp100 protein
Gene ID 20684
UniProt ID O35892

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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