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Rabbit Anti-Rat Citrate Synthase (CS) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for rat citrate synthase. It is purified by protein A. It can be applied to WB, IHC, ICC and IP assays of rat citrate synthase.
Specifications
Target Information
Rat citrate synthase (CS) is a 48-kDa homodimeric enzyme exclusively localized in the mitochondrial matrix of all rat tissues, with elevated expression in high-energy-demand organs (heart, skeletal muscle, kidney). It catalyzes the rate-limiting reaction of the tricarboxylic acid (TCA) cycle, condensing acetyl-CoA and oxaloacetate to form citrate-bridging cytosolic glycolysis with mitochondrial oxidative metabolism. By regulating carbon flux into the TCA cycle, it modulates ATP production, fatty acid biosynthesis, and cellular redox balance, supporting rat physiological processes (e.g., tissue growth, exercise endurance) and adapting to metabolic stress (e.g., nutrient deprivation, mitochondrial impairment). As a core mediator of rat bioenergetics and a canonical mitochondrial marker, CS is a critical target for studying metabolic disorders, mitochondrial pathologies, and tissue energy homeostasis.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.