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Rabbit Anti-Mouse Succinate Dehydrogenase Complex Subunit A (SDHA) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse succinate dehydrogenase complex subunit A. It is purified by protein A. It can be applied to WB, IHC and IF assays of mouse succinate dehydrogenase complex subunit A.
Specifications
Target Information
Mouse Succinate Dehydrogenase Complex Subunit A (SDHA) is the 70 kDa flavoprotein catalytic core of mitochondrial Complex II. It oxidizes succinate to fumarate, concomitantly reducing FAD to FADH₂ and feeding electrons into the respiratory chain. SDHA is expressed in all aerobic tissues, coupling the citric-acid cycle to oxidative phosphorylation and ATP production. Loss-of-function mutations disrupt energy metabolism and elevate succinate, driving pseudohypoxic signaling. As an essential metabolic hub, SDHA is a key target for studies of mitochondrial disease, cancer metabolism, and oxidative stress.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.