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Rabbit Anti-Mouse Podoplanin (PDPN) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse podoplanin. It is purified by protein A. It can be applied to WB, IHC, ICC and IP assays of mouse podoplanin.
Specifications
Target Information
Mouse podoplanin (PDPN) is a 43-kDa transmembrane glycoprotein predominantly expressed in murine lymphatic endothelial cells, podocytes, and certain immune cells (lymphocytes, macrophages). It mediates cell-cell adhesion, cytoskeletal remodeling, and signaling via interactions with C-type lectin-like receptor 2 (CLEC-2). Critical for murine lymphatic vessel development, blood-lymphatic barrier formation, and renal filtration function, it also regulates immune cell trafficking and tumor metastasis in cancer models. Dysregulated expression associates with lymphangiogenesis-related disorders, glomerulopathy, and malignant progression. As a key mediator of lymphatic biology and cell signaling, mouse PDPN is a critical target for studying lymphatic pathobiology, cancer metastasis, and vascular-targeted therapeutics.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.