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Rabbit Anti-Rat Interleukin 1 Receptor Type I (IL1R1) Polyclonal Antibody

Cat. No.VD3N351

Product TypeVeterinary Antibodies

Size

Product Overview

BioVenic rabbit polyclonal antibody is specific for rat interleukin 1 receptor type I. It is purified by protein A. It can be applied to WB, IHC, ICC and IP assays of rat interleukin 1 receptor type I.

Specifications

Application WB; IHC; ICC; IP
Clonality Polyclonal
Classification Primary Antibody
Clone C1N102
Host Rabbit
Target Species Rat
Species Reactivity Rat
Specificity Rat Interleukin 1 Receptor Type I
Isotype IgG
Immunogen Recombinant protein of rat interleukin 1 receptor type I
Purification Purified by Protein A
Concentration 0.5 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.02% Sodium Azide
Buffer Phosphate Buffered Saline, pH 7.4, with 50% glycerol
Physical State Liquid

Target Information

Rat interleukin 1 receptor type I (IL-1R1) is a key receptor involved in the immune response. It targets interleukin-1β (IL-1β), a cytokine that plays a crucial role in inflammation and immune regulation. Binding of IL-1β to IL-1R1 activates intracellular signaling pathways, leading to the production of pro-inflammatory molecules and the regulation of immune cell functions. IL-1R1 is expressed on various immune cells, including macrophages and dendritic cells, and is essential for mounting an effective immune response. Its specific interaction with IL-1β makes it a valuable target for antibody development to enhance detection and monitoring in immunology and inflammatory disease research, supporting studies on immune mechanisms and therapeutic interventions.

Target Rat Interleukin 1 Receptor Type I
Target Synonym CD121a; CD121-A; IL1-R1; IL1R; IL1RA
Gene ID 25663
UniProt ID Q99MF4

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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