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Rabbit Anti-Rat Cytotoxic T-Lymphocyte Associated Antigen 4 (CTLA4) Polyclonal Antibody

Cat. No.VD3N550

Product TypeVeterinary Antibodies

Size

Product Overview

BioVenic rabbit polyclonal antibody is specific for rat cytotoxic T-lymphocyte associated antigen 4. It is purified by protein A. It can be applied to WB, IHC, ICC and IP assays of rat cytotoxic T-lymphocyte associated antigen 4.

Specifications

Application WB; IHC; ICC; IP
Clonality Polyclonal
Classification Primary Antibody
Clone C1N301
Host Rabbit
Target Species Rat
Species Reactivity Rat
Specificity Rat Cytotoxic T-Lymphocyte Associated Antigen 4
Isotype IgG
Immunogen Recombinant protein of rat cytotoxic T-lymphocyte associated antigen 4
Purification Purified by Protein A
Concentration 0.5 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.02% Sodium Azide
Buffer Phosphate Buffered Saline, pH 7.4, with 50% glycerol
Physical State Liquid

Target Information

Rat Cytotoxic T - Lymphocyte Associated Antigen 4 (CTLA - 4) is a key immune checkpoint protein expressed on T cells. It acts as a negative regulator of T cell activation by competing with CD28 for binding to CD80 and CD86 on antigen - presenting cells. CTLA - 4 plays a crucial role in maintaining immune tolerance and preventing excessive immune responses. Its interactions are critical for modulating the balance between immune activation and suppression. CTLA - 4 is a valuable target for studying immune regulation and developing therapeutic strategies for autoimmune diseases and cancer immunotherapy.

Target Rat Cytotoxic T-Lymphocyte Associated Antigen 4
Target Synonym CD152; CELIAC3; CTLA4; GSE; IDDM12
Gene ID 63835
UniProt ID G3V7D2

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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