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Rabbit Anti-Mouse Cluster of Differentiation 19 (CD19) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse cluster of differentiation 19. It is purified by protein A. It can be applied to WB, IHC, ICC and IP assays of mouse cluster of differentiation 19.
Specifications
Target Information
Mouse cluster of differentiation 19 (CD19) is a 95-kDa transmembrane glycoprotein exclusively expressed on mouse B lineage cells-from pro-B cells through mature B cells, with absence on plasma cells. It forms a co-receptor complex with CD21 and CD81, enhancing B cell receptor (BCR) signaling upon antigen binding. This interaction promotes B cell activation, proliferation, differentiation into antibody-secreting cells, and germinal center formation, critical for murine adaptive humoral immunity. Dysregulated expression associates with B cell malignancies and autoimmune diseases. As a definitive B cell-specific marker and key mediator of B cell function, mouse CD19 is a critical target for studying immunology, B cell biology, and immunotherapies targeting B cell-related disorders.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.