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Rabbit Anti-Rat VEGF Co Regulated Chemokine 1 (VCC1) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for rat VEGF co regulated chemokine 1. It is purified by protein A. It can be applied to WB, IHC, ICC and IP assays of rat VEGF co regulated chemokine 1.
Specifications
Target Information
Rat VEGF co-regulated chemokine 1 (VCC-1, CCL21) is a 12-kDa CC chemokine predominantly expressed in rat lymphoid tissues (lymph nodes, spleen), endothelial cells, and inflammatory sites. It binds to CCR7 receptors on T cells, B cells, and dendritic cells, mediating lymphocyte homing to lymphoid organs and directing immune cell trafficking during inflammation. Beyond immune cell recruitment, it modulates angiogenesis by interacting with vascular endothelial cells, supporting vascular remodeling in physiological and pathological contexts. Critical for rat immune surveillance, lymphoid tissue organization, and inflammatory responses, its dysregulation associates with autoimmune diseases, chronic inflammation, and tumor metastasis. As a key mediator of immune cell trafficking and angiogenesis, rat VCC-1 is a critical target for studying immunology, inflammatory pathologies, and cancer immunotherapeutics.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.