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Rabbit Anti-Rat Zona Pellucida Glycoprotein 2 (ZP2) Polyclonal Antibody

Cat. No.VD3N864

Product TypeVeterinary Antibodies

Size

Product Overview

BioVenic rabbit polyclonal antibody is specific for rat zona pellucida glycoprotein 2, sperm receptor. It is purified by protein A. It can be applied to WB, IHC, ICC and IP assays of rat zona pellucida glycoprotein 2, sperm receptor.

Specifications

Application WB; IHC; ICC; IP
Clonality Polyclonal
Classification Primary Antibody
Clone C2N264
Host Rabbit
Target Species Rat
Species Reactivity Rat
Specificity Rat Zona Pellucida Glycoprotein 2, Sperm Receptor
Isotype IgG
Immunogen Recombinant protein of rat zona pellucida glycoprotein 2, sperm receptor
Purification Purified by Protein A
Concentration 1 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.05% Proclin 300
Buffer 0.01M Phosphate Buffered Saline, pH 7.4, with 50% glycerol
Physical State Liquid

Target Information

Rat zona pellucida glycoprotein 2 (ZP2), a 120-kDa sperm receptor, is a core component of the rat oocyte zona pellucida (ZP)-a extracellular matrix surrounding maturing oocytes in the ovary. It mediates species-specific sperm-oocyte binding and initial fertilization events via interactions with sperm surface proteins. Beyond fertilization, ZP2 contributes to ZP structural integrity, preventing polyspermy and supporting early embryonic development in rats. Critical for rat reproductive success, its dysregulated expression or structural alterations associate with infertility and fertilization failure. As a key mediator of gamete interaction and reproductive competence, rat ZP2 is a critical target for studying reproductive biology and developing contraceptive or fertility-enhancing therapeutics.

Target Rat Zona Pellucida Glycoprotein 2, Sperm Receptor
Target Synonym ZPA; Zona Pellucida Sperm-Binding Protein 2; Zona pellucida protein A
Gene ID 81828
UniProt ID O54767

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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