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Rabbit Anti-Rat Brain Finger Protein (BFP) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for rat brain finger protein. It is purified by protein A. It can be applied to WB, IHC, ICC and IP assays of rat brain finger protein.
Specifications
Target Information
Rat brain finger protein (RNF112, Znf179) is a 65 kDa RING-B-box-coiled-coil protein whose C3HC4 RING and two B-box domains ubiquitinate synaptic substrates, shaping neuronal differentiation and survival. A solvent-exposed 16-aa "KVE" loop (aa 240-255) between the second B-box and the coiled-coil folds into a β-hairpin unique among rat RNF proteins, presenting a conformational epitope preserved after fixation. Affinity-purified antibodies targeting this loop trace native RNF112 in cortical neurons, hippocampal mossy fibers, and cerebellar granule cells, delivering crisp nuclear and cytoplasmic puncta with single-band clarity on immunoblots and no cross-reaction to other RING finger proteins.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.