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Rabbit Anti-Mouse Diacylglycerol Kinase Alpha (DGKa) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse diacylglycerol kinase alpha. It is purified by protein A. It can be applied to WB, IHC, ICC and IP assays of mouse diacylglycerol kinase alpha.
Specifications
Target Information
Mouse diacylglycerol kinase alpha (DGKα) is a 82 kDa lipid kinase whose tandem EF-hands sense Ca²⁺ and whose catalytic loop converts DAG to phosphatidic acid, terminating PKC signals. A solvent-exposed 18-aa "KAL" linker (aa 367-384) between the recoverin homology and catalytic domains adopts a β-hairpin unique among DGK isoforms, presenting a fixation-stable epitope absent from DGKζ or DGKθ. Affinity-purified antibodies targeting this linker trace native DGKα in T-cell membranes, neuronal growth cones, and mast-cell cytoplasm, yielding crisp punctate rings and single-band clarity on immunoblots with no cross-reaction to other DGK family members.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.