This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Rabbit Anti-Mouse Complement Factor H (CFH) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse complement factor H. It is purified by protein A. It can be applied to WB, IHC, ICC and IP assays of mouse complement factor H.
Specifications
Target Information
Mouse complement factor H, a 155 kDa soluble glycoprotein built from 20 short consensus repeats, patrols plasma and endothelial surfaces to restrain the alternative pathway. By competing with factor B for C3b binding, accelerating decay of C3 and C5 convertases, and serving as cofactor for factor I-mediated C3b cleavage, it shields host cells from unintended complement damage. Abundant in serum, kidney and liver, its loss or mutation unleashes uncontrolled C3 activation; thus, factor H is a valued ELISA, Western blot or immunostaining target for tracing complement dysregulation in glomerulonephritis, hemolytic uremic syndrome and age-related macular degeneration models .
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.