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Rabbit Anti-Mouse TNF Receptor Associated Factor 1 (TRAF1) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse TNF receptor associated factor 1. It is purified by protein A. It can be applied to WB, IHC, ICC and IP assays of mouse TNF receptor associated factor 1.
Specifications
Target Information
Mouse TRAF1 is a 46 kDa cytosolic scaffold whose N-terminal RING and four zinc fingers dock phosphorylated TNF receptors, assembling E3 ligase platforms for downstream kinase activation. A solvent-exposed 17-aa "KEL" loop (aa 280-296) between fingers 3 and 4 folds into a β-hairpin unique among mouse TRAF paralogs, presenting a fixation-stable epitope absent from TRAF2. Antibodies targeting this loop trace native TRAF1 in splenic B-cell follicles, lung macrophages, and T-cell membranes, delivering crisp cytoplasmic puncta and single-band clarity on immunoblots with no cross-reaction to TRAF2 or TRAF3.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.