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Rabbit Anti-Rat Carbonic Anhydrase VI (CA6) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for rat carbonic anhydrase VI. It is purified by protein A. It can be applied to WB, IHC, ICC and IP assays of rat carbonic anhydrase VI.
Specifications
Target Information
Rat carbonic anhydrase VI (CA-VI) is a 37 kDa secreted zinc metalloenzyme whose funnel-shaped active site interconverts CO₂ and bicarbonate, buffering saliva and airway fluid. A solvent-exposed 16-aa "KVE" loop (aa 185-200) between β7 and α5 folds into a β-hairpin unique among rat CA isoforms, presenting a conformational epitope preserved after deglycosylation and fixation. Affinity-purified antibodies targeting this loop trace native CA-VI in parotid acinar cells, salivary ducts, and tracheal epithelium, delivering crisp apical granules and single-band clarity on immunoblots with no cross-reaction to cytosolic CA-I or CA-II.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.