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Mouse Growth Factor, Augmenter of Liver Regeneration (GFER) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Growth Factor, Augmenter of Liver Regeneration (GFER) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse GFER in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Growth Factor, Augmenter Of Liver Regeneration, also known as FAD-linked sulfhydryl oxidase ALR, is a FAD-dependent sulfhydryl oxidase that restores redox-active disulfide bonds in CHCHD4/MIA40. This chaperone is crucial for disulfide bond formation and protein folding within the mitochondrial intermembrane space. In mice, FAD-linked sulfhydryl oxidase ALR primarily facilitates the catalysis of disulfide bond formation, maintains redox balance, enhances cell proliferation, and shields hepatocytes from damage. Initially discovered in connection with mouse liver regeneration, ALR is a FAD-dependent thioredoxin oxidase that plays a significant role in liver regeneration. It aids in the survival and proliferation of liver cells by catalyzing disulfide bond formation and promoting the oxidative folding of proteins.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Gala, Khushboo S, and Vatsalya Vatsalya. "Emerging Noninvasive Biomarkers, and Medical Management Strategies for Alcoholic Hepatitis: Present Understanding and Scope." Cells vol. 9,3 524. 25 Feb. 2020.