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Mouse Signal Transducer And Activator of Transcription 4 (STAT4) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Signal Transducer And Activator of Transcription 4 (STAT4) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse STAT4 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Signal transducer and activator of transcription 4 (STAT4) is a transcriptional regulator primarily expressed in hematopoietic cells, playing a pivotal role in cellular growth, differentiation, and immune response. It is essential for the differentiation of T-helper 1 cells and the production of interferon-gamma. STAT4 is a crucial transcription factor in the IL-12 and IL-23 signaling pathways, which are important for activating Th1 cells and regulating immune responses. Mice deficient in STAT4 exhibit reduced immune responses in specific disease models, such as experimental autoimmune encephalomyelitis (EAE), where the absence of STAT4 leads to decreased Th17 cell differentiation and a reduced inflammatory response.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.