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Bovine Protein Disulfide-Isomerase A4 (PDIA4) ELISA Kit-Sandwich
Product Overview
BioVenic Bovine Protein Disulfide-Isomerase A4 (PDIA4) ELISA Kit-Sandwich is designed for the quantitative determination of Bovine Protein Disulfide-Isomerase A4 (PDIA4) in serum, plasma, tissue homogenate, cell culture supernatant, cell extract, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Protein Disulfide-Isomerase A4 (PDIA4), also known as carnosine dipeptidase 2, is an enzyme encoded by the PDIA4 gene in cattle. PDIA4 plays a critical role in the endoplasmic reticulum stress (ERS) response. Specifically, it regulates glioblastoma (GBM)-specific pro-angiogenesis. PDIA4 is associated with the secretion of vascular endothelial growth factor-A (VEGF-A) by GBM cells. PDIA4 has been characterized as a crucial regulator of β-cell pathogenesis and diabetes, suggesting PDIA4 is a novel therapeutic and diagnostic target of diabetes.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Kuo, T. F. et al. Pdia4 regulates β-cell pathogenesis in diabetes: molecular mechanism and targeted therapy. EMBO molecular medicine. 2021, 13: e11668.