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Mouse Glutamine Synthetase (GS) ELISA Kit-Sandwich

Cat. No.EK6F824

Product TypeAnimal Immunoassay Kits

Size

Product Overview

BioVenic Mouse Glutamine Synthetase (GS) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse GS in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Mouse Glutamine Synthetase (GS).
Target Species Mouse
Species Reactivity Mouse
Detection Range 15.7-1000 pg/mL
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 12%
Assay Time Around 90 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids.

Target Information

Glutamine synthetase (GS) is a crucial enzyme in mice, primarily involved in glutamine synthesis and playing a significant role in various physiological and pathological processes. GS catalyzes the conversion of glutamate and ammonia into glutamine, a process vital for maintaining intracellular nitrogen balance, amino acid metabolism, and ammonia detoxification. As the only enzyme capable of synthesizing glutamine de novo, GS activity is evident in numerous tissues, including muscle, liver, kidney, and brain. In muscle tissue, GS aids in coping with starvation and extrahepatic ammonia detoxification by facilitating glutamine production. For example, during starvation, GS activity significantly increases to support glutamine synthesis, thereby maintaining overall metabolic balance. In mice, GS is essential for ammonia detoxification, mitigating ammonia's toxic effects on the nervous system by converting glutamate and ammonia into glutamine.

Target/Biomarker Mouse GS
Target Synonym GLNS; GLUL; Glutamate-Ammonia Ligase; Glutamate decarboxylase

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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