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Mouse Proto-Oncogene Wnt-1 (WNT1) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Proto-Oncogene Wnt-1 (WNT1) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse WNT1 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Proto-oncogene Wnt-1 serves as a ligand for the frizzled family of seven transmembrane receptors and operates within the canonical Wnt signaling pathway by facilitating beta-catenin-dependent transcriptional activation. Wnt1 plays a crucial role in the skeletal system by promoting bone formation and mineralization through the activation of osteoblasts. For instance, one study demonstrated that conditionally knocking out Wnt1 in osteoblasts and using osteoblast-specific expression models led to spontaneous fractures and severe osteopenia (67% fracture rate) in mice. Conversely, overexpression of Wnt1 significantly boosted bone volume and density, underscoring its importance in maintaining bone homeostasis.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.