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Rabbit Anti-Mouse Sphingosine 1 Phosphate Lyase 1 (SGPL1) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse sphingosine 1 phosphate lyase 1. It is purified by protein A. It can be applied to WB, IHC, ICC and IP assays of mouse sphingosine 1 phosphate lyase 1.
Specifications
Target Information
Mouse Sphingosine-1-phosphate Lyase 1 (SGPL1) is an ER-associated enzyme that irreversibly cleaves sphingosine-1-phosphate (S1P) into hexadecenal and phosphoethanolamine, terminating S1P signaling. Highly expressed in brain, spleen, and thymus, it controls lymphocyte trafficking, vascular integrity, and lipid homeostasis. Loss of SGPL1 activity elevates S1P pools, disrupting immune cell egress and vascular permeability. As a critical modulator of sphingolipid metabolism, SGPL1 is an important target for studies of immune regulation, angiogenesis, and metabolic disorders.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.