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Rabbit Anti-Rat Transcription Factor A (TFAM) Polyclonal Antibody

Cat. No.VD3N321

Product TypeVeterinary Antibodies

Size

Product Overview

BioVenic rabbit polyclonal antibody is specific for rat transcription factor A. It is purified by protein A. It can be applied to WB, IHC, ICC and IP assays of rat transcription factor A.

Specifications

Application WB; IHC; ICC; IP
Clonality Polyclonal
Classification Primary Antibody
Clone C1N72
Host Rabbit
Target Species Rat
Species Reactivity Rat
Specificity Rat Transcription Factor A
Isotype IgG
Immunogen Recombinant protein of rat transcription factor A
Purification Purified by Protein A
Concentration 0.5 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.05% Proclin 300
Buffer 0.01M Phosphate Buffered Saline, pH 7.4, with 50% glycerol
Physical State Liquid

Target Information

Rat Transcription Factor A, Mitochondrial (TFAM) is a nuclear-encoded protein essential for mitochondrial DNA (mtDNA) maintenance and transcription. It binds to mtDNA, facilitating replication and ensuring proper mitochondrial function. TFAM is highly expressed in tissues with high energy demands, such as the heart and skeletal muscle. Targeting TFAM with specific antibodies allows for detailed investigation of its role in mitochondrial biology, making it a valuable tool for studying energy metabolism and related diseases.

Target Rat Transcription Factor A
Target Synonym MtTF1; TCF6; TCF6L2; mtTFA; Mitochondrial transcription factor 1
Gene ID 83474
UniProt ID Q91ZW1

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Piantadosi, Claude A., and Hagir B. Suliman. "Mitochondrial transcription factor A induction by redox activation of nuclear respiratory factor 1." Journal of Biological Chemistry 281.1 (2006): 324-333. https://doi.org/10.1074/jbc.M508805200
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