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Rabbit Anti-Mouse Apolipoprotein E (APOE) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse apolipoprotein E. It is purified by protein A. It can be applied to WB, IHC, ICC and IP assays of mouse apolipoprotein E.
Specifications
Target Information
Mouse apolipoprotein E (ApoE) is a 34-kDa glycoprotein primarily synthesized in the liver and brain. It plays a central role in lipid metabolism, mediating cholesterol and triglyceride transport via interactions with low-density lipoprotein receptors. Expressed in astrocytes, microglia, and hepatocytes, ApoE regulates lipid homeostasis and cellular cholesterol efflux. Its three isoforms (ApoE2, ApoE3, ApoE4) exhibit distinct functional properties, with isoform-specific effects on lipid clearance and tissue integrity. As a key mediator of lipid transport and neuroinflammation, mouse ApoE serves as a critical target for investigating lipid-related disorders and neurodegenerative disease mechanisms.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.