This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Rabbit Anti-Mouse Growth Differentiation Factor 7 (GDF7) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse growth differentiation factor 7. It is purified by protein A. It can be applied to WB, IHC, ICC and IP assays of mouse growth differentiation factor 7.
Specifications
Target Information
Mouse growth differentiation factor 7 (GDF-7, BMP-12) is a 42 kDa disulfide-linked homodimer whose C-terminal TGF-β knot engages BMPR-II and ALK2/3 to drive tendon and cartilage lineage commitment. A solvent-exposed 14-residue "SKP" loop (aa 95-108) between pre-helix 1 and β2 folds into a β-hairpin unique among mouse GDF/BMP isoforms, presenting a conformational epitope preserved in both pro- and mature forms. Affinity-purified antibodies targeting this loop trace native GDF-7 in embryonic tendons, ligament fibroblasts, and osteoblastic progenitors, delivering crisp extracellular deposition and single-band clarity on immunoblots with no cross-reaction to BMP-2 or GDF-5.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.