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Rabbit Anti-Mouse Receptor For Advanced Glycation Endproducts (RAGE) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse receptor for advanced glycation endproducts. It is purified by protein A. It can be applied to WB, IHC, ICC and IP assays of mouse receptor for advanced glycation endproducts.
Specifications
Target Information
Mouse receptor for advanced glycation end-products (RAGE) is a 45 kDa multi-ligand pattern-recognition receptor that targets high-mobility group box 1, S100/calgranulins and AGE-modified proteins, activating NF-κB and MAPK cascades to propagate oxidative stress and inflammation. Its extracellular V-type Ig domain presents a unique, species-restricted epitope ideal for antibody generation; anti-RAGE immunoreagents detect membrane-bound and soluble forms in lung, vasculature and inflamed tissues without cross-reacting with other Ig-superfamily receptors, providing a precise read-out of chronic inflammatory and metabolic signaling.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.