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Rabbit Anti-Mouse Granzyme D (GZMD) Polyclonal Antibody

Cat. No.VD3N384

Product TypeVeterinary Antibodies

Size

Product Overview

BioVenic rabbit polyclonal antibody is specific for mouse granzyme D. It is purified by protein A. It can be applied to WB, IHC, ICC and IP assays of mouse granzyme D.

Specifications

Application WB; IHC; ICC; IP
Clonality Polyclonal
Classification Primary Antibody
Clone C1N135
Host Rabbit
Target Species Mouse
Species Reactivity Mouse
Specificity Mouse Granzyme D
Isotype IgG
Immunogen Recombinant protein of mouse granzyme D
Purification Purified by Protein A
Concentration 0.5 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.02% Sodium Azide
Buffer Phosphate Buffered Saline, pH 7.4, with 50% glycerol
Physical State Liquid

Target Information

Mouse granzyme D is a serine protease involved in immune responses. It targets the induction of apoptosis in target cells, particularly in the context of cytotoxic T lymphocytes (CTLs) and natural killer (NK) cells. Granzyme D is released into the immunological synapse, where it cleaves specific substrates, leading to cell death. This process is crucial for eliminating infected or transformed cells. Its specific interaction with cellular substrates makes it a valuable target for antibody development to enhance detection and monitoring in immunology and cancer research, supporting studies on immune-mediated cell death and related pathologies.

Target Mouse Granzyme D
Gene ID 14941
UniProt ID P11033

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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