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Rabbit Anti-Rat Growth Hormone Receptor (GHR) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for rat growth hormone receptor. It is purified by protein A. It can be applied to WB, IHC, ICC and IP assays of rat growth hormone receptor.
Specifications
Target Information
Rat growth hormone receptor (GHR) is a 95 kDa single-pass cytokine receptor whose extracellular domain grips GH through two tryptophan clamps, while Box-1/2 motifs recruit JAK2 for STAT phosphorylation. A solvent-exposed 18-aa "KVE" loop (aa 192-209) between fibronectin type III repeats folds into a β-hairpin unique among rat cytokine receptors, presenting a fixation-stable epitope absent from prolactin receptor. Affinity-purified antibodies targeting this loop trace native GHR in hepatic sinusoids, chondrocyte membranes, and adipocyte sarcolemma, delivering crisp surface rings and single-band clarity on immunoblots with no cross-reaction to PRL-R or leptin receptor.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.