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Rabbit Anti-Mouse Glucosidase Alpha Acid (GaA) Polyclonal Antibody

Cat. No.VD3N386

Product TypeVeterinary Antibodies

Size

Product Overview

BioVenic rabbit polyclonal antibody is specific for mouse glucosidase alpha acid. It is purified by protein A. It can be applied to WB, IHC, ICC and IP assays of mouse glucosidase alpha acid.

Specifications

Application WB; IHC; ICC; IP
Clonality Polyclonal
Classification Primary Antibody
Clone C1N137
Host Rabbit
Target Species Mouse
Species Reactivity Mouse
Specificity Mouse Glucosidase Alpha Acid
Isotype IgG
Immunogen Recombinant protein of mouse glucosidase alpha acid
Purification Purified by Protein A
Concentration 0.59 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.05% Proclin 300
Buffer 0.01M Phosphate Buffered Saline, pH 7.4, with 50% glycerol
Physical State Liquid

Target Information

Mouse glucosidase alpha, acid (GAA) is a lysosomal enzyme that targets the breakdown of glycogen. It plays a crucial role in preventing the accumulation of glycogen in lysosomes, which can lead to cellular dysfunction. GAA catalyzes the hydrolysis of glycogen into glucose, maintaining cellular homeostasis. Deficiencies in GAA are associated with Pompe disease, a severe lysosomal storage disorder. The specific interaction of GAA with glycogen makes it a valuable target for antibody development to enhance detection and monitoring in metabolic studies and lysosomal storage disorder research, supporting investigations into glycogen metabolism and related pathologies.

Target Mouse Glucosidase Alpha Acid
Target Synonym LYAG; Acid Alpha-Glucosidase; Lysosomal Alpha-Glucosidase; Pompe Disease Glycogen Storage Disease Type II; Acid Maltase
Gene ID 14387
UniProt ID P70699

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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