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Mouse Laminin Alpha 5 (LAMa5) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Laminin Alpha 5 (LAMa5) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse LAMa5 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
The Laminin α5 subunit in mice is crucial for various biological processes and developmental phases, primarily influencing tissue patterning, organogenesis, and the structure and functionality of the extracellular matrix. It plays a significant role in embryonic development. Mice lacking the Lama5 gene exhibit several developmental abnormalities, such as improper neural tube closure (exencephaly), fusion of digits (syndactyly), and abnormal placental formation. Furthermore, the Laminin α5 chain is vital for the proper development of intestinal smooth muscle. In mice with a knocked-out Lama5 gene, there is excessive folding of intestinal loops, delayed marker expression, and impaired intestinal development.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Ritié, Léa et al. "Abnormal Wnt and PI3Kinase signaling in the malformed intestine of lama5 deficient mice." PloS one vol. 7,5 (2012): e37710.