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Mouse Cyclophilin D (CyPD) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Cyclophilin D (CyPD) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse CyPD in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Cyclophilin D (CypD) is a mitochondrial enzyme known as a peptidyl-prolyl cis-trans isomerase that plays a crucial role in controlling the mitochondrial permeability transition pore (PTP). The PTP is a non-specific channel that, when opened, can result in cell death. This process is associated with ischemia/reperfusion injuries across various organs, neurodegenerative diseases, and muscular dystrophies. Studies have demonstrated that mice lacking Cyclophilin D do not accumulate succinate during cardiac ischemia. CypD-deficient mice exhibit a higher propensity for myocardial fibrosis and heart failure under conditions of cardiac stress.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.