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Mouse Intercellular Adhesion Molecule 2 (ICAM2) ELISA Kit-Sandwich

Cat. No.EK5F480

Product TypeAnimal Immunoassay Kits

Size

Product Overview

BioVenic Mouse Intercellular Adhesion Molecule 2 (ICAM2) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse ICAM2 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Mouse Intercellular Adhesion Molecule 2 (ICAM2).
Target Species Mouse
Species Reactivity Mouse
Detection Range 0.17-10 ng/mL
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 12%
Assay Time Around 90 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids.

Target Information

ICAM proteins serve as ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). ICAM-2 may contribute to lymphocyte recirculation by inhibiting LFA-1-dependent cell adhesion. It facilitates adhesive interactions crucial for antigen-specific immune responses, NK cell-mediated clearance, lymphocyte recirculation, and other cellular interactions essential for immune surveillance and response. ICAM-2 also plays a significant role in inflammation. For instance, in the laser-induced choroidal neovascularization (CNV) model, ICAM-2 expression is closely linked to the recruitment of inflammatory cells. Studies have shown that the absence of ICAM-2 decreases the recruitment of inflammatory cells, such as macrophages, thereby significantly inhibiting CNV development.

Target/Biomarker Mouse ICAM2
Target Synonym CD102
Gene ID 15896
UniProt ID P35330

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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