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Mouse Intercellular Adhesion Molecule 2 (ICAM2) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Intercellular Adhesion Molecule 2 (ICAM2) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse ICAM2 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
ICAM proteins serve as ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). ICAM-2 may contribute to lymphocyte recirculation by inhibiting LFA-1-dependent cell adhesion. It facilitates adhesive interactions crucial for antigen-specific immune responses, NK cell-mediated clearance, lymphocyte recirculation, and other cellular interactions essential for immune surveillance and response. ICAM-2 also plays a significant role in inflammation. For instance, in the laser-induced choroidal neovascularization (CNV) model, ICAM-2 expression is closely linked to the recruitment of inflammatory cells. Studies have shown that the absence of ICAM-2 decreases the recruitment of inflammatory cells, such as macrophages, thereby significantly inhibiting CNV development.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.